Cartoon diagram of a Thermotoga maritima bacterium flavin-dependent thymidylate synthase, or FDTS, enzyme, which is an example of the class of FDTS enzymes. The FDTS enzyme is coded by the thyX gene and has been found primarily in bacteria and viruses, including several human pathogens and biological warfare agents. The two compounds involved in the active site of the enzymatic reaction, FAD and deoxy-uridine monophosphate, are represented by the small bluish-purple and red grouped spheres, respectively, and are enclosed by four protein sub-units depicted by green, light blue, gold and pink magenta ribbon-like structures.Credit: Amnon Kohen, University of Iowa
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